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Bettendorff 2008 benfotiamine, a synthetic s-acyl thiamine derivative, has different mechanisms of action and a different pharmacological profile than lipid-soluble thiamine disulfide derivatives.

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Benfotiamine however, can be taken safely at much higher dosage as it is fat-soluble, not water soluble like thiamine.

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Thus benfotiamine should not be classified as a lipophilic compound as many authors still do 10 , 24 , 25 , 38 .

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Benfotiamine but not fursultiamine reduces the formation of amyloid plaques in app ps1 mice.

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Benfotiamine is especially helpful lady-era in treating alcoholic neuropathy, but the best way to use benfotiamine for nerve damage depends on the source of the nerve damage.

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16 benfotiamine 70mg kg oral ingestion for four weeks was later shown to preserve signalling via an akt pim-1 pathway pi3k dependent secondary to its transketolase inducing ability.

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